› 1rh8

Solution NMR

Three-dimensional structure of the calcium-free Piccolo C2A-domain

Released:
DOI: 10.2210/pdb1rh8/pdb
PDB entry 1rh8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1rh8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1rh8 coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Primary publication:
A conformational switch in the Piccolo C2A domain regulated by alternative splicing.
Garcia J, Gerber SH, Sugita S, Südhof TC, Rizo J
Nat Struct Mol Biol 11 45-53 (2004)
PMID: 14718922

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191632 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein piccolo Chain: A
Molecule details ›
Chain: A
Length: 142 amino acids
Theoretical weight: 16.48 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9JKS6 (Residues: 4635-4776; Coverage: 3%)
Gene name: Pclo
Sequence domains: C2 domain
Structure domains: C2 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

The presynaptic active zone.
Südhof TC. (2012)
14 more

1 mention without citation

Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.
Gundelfinger et al. (2015)