1ru9

X-ray diffraction
2.5Å resolution

Crystal Structure (A) of u.v.-irradiated cationic cyclization antibody 4C6 Fab at pH 4.6 with a data set collected in-house.

Released:
Source organism: Mus musculus

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-208650 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
immunoglobulin igg2a, light chain Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.24 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
Immunoglobulin heavy constant gamma 2A Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 23.83 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01865 (Residues: 1-102; Coverage: 26%)
Gene names: Igh-1a, Ighg2a
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins

Ligands and Environments

3 bound ligands:
2 modified residues:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU FR-D
Spacegroup: P41212
Unit cell:
a: 64.073Å b: 64.073Å c: 266.041Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.192 0.192 0.247