› 1tfp

X-ray diffraction
2.9Å resolution

TRANSTHYRETIN (FORMERLY KNOWN AS PREALBUMIN)

Released:
DOI: 10.2210/pdb1tfp/pdb
PDB entry 1tfp coloured by chain, front view.
PDB entry 1tfp coloured by chain, side view.
PDB entry 1tfp coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
The crystal structure of transthyretin from chicken.
Sunde M, Richardson SJ, Chang L, Pettersson TM, Schreiber G, Blake CC
Eur J Biochem 236 491-9 (1996)
PMID: 8612621

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-151065 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transthyretin Chains: A, B
Molecule details ›
Chains: A, B
Length: 130 amino acids
Theoretical weight: 14.18 KDa
Source organism: Gallus gallus
UniProt:
  • Canonical: P27731 (Residues: 21-150; Coverage: 100%)
Gene name: TTR
Sequence domains: HIUase/Transthyretin family
Structure domains: Transthyretin/hydroxyisourate hydrolase domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P6522
Unit cell:
a: 77.66Å b: 77.66Å c: 161.041Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 not available

Quick links

Citations

11 review citations

Evolution of the thyroid hormone-binding protein, transthyretin.
Power et al. (2000)
10 more

6 mentions without citation

Predicting the accuracy of protein-ligand docking on homology models.
Bordogna et al. (2011)
5 more