› 1ti8

X-ray diffraction
3Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179722 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemagglutinin Chain: A
Molecule details ›
Chain: A
Length: 314 amino acids
Theoretical weight: 34.29 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: Q6GYW3 (Residues: 21-334; Coverage: 56%)
Sequence domains: Haemagglutinin
Structure domains:
Hemagglutinin Chain: B
Molecule details ›
Chain: B
Length: 172 amino acids
Theoretical weight: 19.95 KDa
Source organism: Influenza A virus
UniProt:
  • Canonical: Q701T7 (Residues: 340-511; Coverage: 31%)
Gene name: HA
Sequence domains: Haemagglutinin
Structure domains: Hemagglutinin Ectodomain; Chain B

Ligands and Environments

3 bound ligands:
Ligand NDG 1 x NDG
Ligand MAN 5 x MAN
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R32
Unit cell:
a: 118.2Å b: 118.2Å c: 298.7Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.23 0.3

Quick links

Citations

27 review citations

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
26 more

22 mentions without citation

Unraveling virus relationships by structure-based phylogenetic classification.
Ng et al. (2020)
21 more