› 1toq

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF A GALACTOSE SPECIFIC LECTIN FROM ARTOCARPUS HIRSUTA IN COMPLEX WITH METHYL-a-D-GALACTOSE

Released:
DOI: 10.2210/pdb1toq/pdb
PDB entry 1toq coloured by chain, front view.
PDB entry 1toq coloured by chain, side view.
PDB entry 1toq coloured by chain, top view.
Source organisms:
Primary publication:
Two orthorhombic crystal structures of a galactose-specific lectin from Artocarpus hirsuta in complex with methyl-alpha-D-galactose.
Rao KN, Suresh CG, Katre UV, Gaikwad SM, Khan MI
Acta Crystallogr D Biol Crystallogr 60 1404-12 (2004)
PMID: 15272163

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
hetero octamer
hetero tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-148424 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Agglutinin alpha chain Chains: A, C, E, G
Molecule details ›
Chains: A, C, E, G
Length: 133 amino acids
Theoretical weight: 14.61 KDa
Source organism: Artocarpus hirsutus
UniProt:
  • Canonical: P18670 (Residues: 1-133; Coverage: 100%)
Sequence domains: Jacalin-like lectin domain
Structure domains: Jacalin-like lectin domain
Agglutinin beta-3 chain Chains: B, D, F, H
Molecule details ›
Chains: B, D, F, H
Length: 20 amino acids
Theoretical weight: 2.06 KDa
Source organism: Artocarpus integer
Expression system: Not provided
UniProt:
  • Canonical: P18673 (Residues: 1-20; Coverage: 100%)

Ligands and Environments

1 bound ligand:
Ligand AMG 4 x AMG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 92.372Å b: 98.655Å c: 164.884Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.197 0.235
Expression system: Not provided

Quick links

Citations

12 citation in other articles

Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Ziółkowska et al. (2006)
11 more

1 mention without citation

Ipomoelin, a jacalin-related lectin with a compact tetrameric association and versatile carbohydrate binding properties regulated by its N terminus.
Chang et al. (2012)