› 1txm

Solution NMR

SCORPION TOXIN (MAUROTOXIN) FROM SCORPIO MAURUS, NMR, 35 STRUCTURES

Released:
DOI: 10.2210/pdb1txm/pdb
PDB entry 1txm coloured by chain, ensemble of 35 models, front view.
PDB entry 1txm coloured by chain, ensemble of 35 models, side view.
PDB entry 1txm coloured by chain, ensemble of 35 models, top view.
Source organism: Scorpio maurus
Primary publication:
Solution structure of maurotoxin, a scorpion toxin from Scorpio maurus, with high affinity for voltage-gated potassium channels.
Blanc E, Sabatier JM, Kharrat R, Meunier S, el Ayeb M, Van Rietschoten J, Darbon H
Proteins 29 321-33 (1997)
PMID: 9365987

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160448 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Potassium channel toxin alpha-KTx 6.2 Chain: A
Molecule details ›
Chain: A
Length: 35 amino acids
Theoretical weight: 3.63 KDa
Source organism: Scorpio maurus
Expression system: Not provided
UniProt:
  • Canonical: P80719 (Residues: 1-34; Coverage: 100%)
Sequence domains: Scorpion short toxin, BmKK2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry
Expression system: Not provided

Quick links

Citations

7 review citations

K+ channels as targets for specific immunomodulation.
Chandy et al. (2004)
6 more

9 mentions without citation

Computational methods of studying the binding of toxins from venomous animals to biological ion channels: theory and applications.
Gordon et al. (2013)
8 more