› 1ueg

X-ray diffraction
2.4Å resolution

Crystal structure of amino-terminal microtubule binding domain of EB1

Released:
DOI: 10.2210/pdb1ueg/pdb
PDB entry 1ueg coloured by chain, front view.
PDB entry 1ueg coloured by chain, side view.
PDB entry 1ueg coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the amino-terminal microtubule-binding domain of end-binding protein 1 (EB1).
Hayashi I, Ikura M
J Biol Chem 278 36430-4 (2003)
PMID: 12857735

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172375 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Microtubule-associated protein RP/EB family member 1 Chain: A
Molecule details ›
Chain: A
Length: 130 amino acids
Theoretical weight: 15.05 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15691 (Residues: 1-130; Coverage: 49%)
Gene name: MAPRE1
Sequence domains: Calponin homology (CH) domain
Structure domains: Calponin-like domain

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X12C
Spacegroup: P43212
Unit cell:
a: 48.589Å b: 48.589Å c: 90.301Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.223 0.223 0.279
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

25 review citations

Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
Akhmanova et al. (2008)
24 more