› 1uz6

X-ray diffraction
2.05Å resolution

anti-Lewis X Fab fragment uncomplexed

Released:
DOI: 10.2210/pdb1uz6/pdb
PDB entry 1uz6 coloured by chain, front view.
PDB entry 1uz6 coloured by chain, side view.
PDB entry 1uz6 coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Structure of an anti-Lewis X Fab fragment in complex with its Lewis X antigen.
van Roon AM, Pannu NS, de Vrind JP, van der Marel GA, van Boom JH, Hokke CH, Deelder AM, Abrahams JP
Structure 12 1227-36 (2004)
PMID: 15242599

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-213101 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
IGG FAB (IGG3, KAPPA) LIGHT CHAIN 291-2G3-A Chains: E, L, M, V
Molecule details ›
Chains: E, L, M, V
Length: 218 amino acids
Theoretical weight: 24.09 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins
IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A Chains: F, H, P, W
Molecule details ›
Chains: F, H, P, W
Length: 217 amino acids
Theoretical weight: 23.43 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

1 bound ligand:
Ligand SO4 4 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P1
Unit cell:
a: 67.405Å b: 71.559Å c: 104.79Å
α: 86.48° β: 71.32° γ: 83.26°
R-values:
R R work R free
0.198 0.198 0.244

Quick links

Citations

7 review citations

Antibody recognition of carbohydrate epitopes†.
Haji-Ghassemi et al. (2015)
6 more

4 mentions without citation

Blind prediction performance of RosettaAntibody 3.0: grafting, relaxation, kinematic loop modeling, and full CDR optimization.
Weitzner et al. (2014)
3 more