› 1vb8

Solution NMR

solution structure of vhr1, the first cyclotide from root tissue

Released:
DOI: 10.2210/pdb1vb8/pdb
PDB entry 1vb8 coloured by chain, ensemble of 20 models, front view.
PDB entry 1vb8 coloured by chain, ensemble of 20 models, side view.
PDB entry 1vb8 coloured by chain, ensemble of 20 models, top view.
Source organism: Viola hederacea
Primary publication:
Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.
Trabi M, Craik DJ
Plant Cell 16 2204-16 (2004)
PMID: 15295104

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160777 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Root cyclotide 1 Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.14 KDa
Source organism: Viola hederacea
UniProt:
  • Canonical: P83937 (Residues: 4-30; Coverage: 90%)
Sequence domains: Cyclotide family

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing

Quick links

Citations

14 review citations

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.
Craik et al. (2006)
13 more

2 mentions without citation

Host-defense activities of cyclotides.
Craik DJ. (2012)
1 more