› 1vjt

X-ray diffraction
2.5Å resolution

Crystal structure of Alpha-glucosidase (TM0752) from Thermotoga maritima at 2.50 A resolution

Released:
DOI: 10.2210/pdb1vjt/pdb
PDB entry 1vjt coloured by chain, front view.
PDB entry 1vjt coloured by chain, side view.
PDB entry 1vjt coloured by chain, top view.
Source organism: Thermotoga maritima
Entry author: Joint Center for Structural Genomics (JCSG)

Function and Biology Details

Reaction catalysed: 
An alpha-D-glucuronoside + H(2)O = an alcohol + D-glucuronate
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194618 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glycosyl hydrolase family 4 C-terminal domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 483 amino acids
Theoretical weight: 57.6 KDa
Source organism: Thermotoga maritima
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9WZL1 (Residues: 1-471; Coverage: 100%)
Gene name: TM_0752
Sequence domains:
Structure domains: NAD(P)-binding Rossmann-like Domain

Ligands and Environments

1 bound ligand:
Ligand NAD 1 x NAD
1 modified residue:
Ligand MSE 15 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 75.722Å b: 79.815Å c: 89.222Å
α: 90° β: 101.99° γ: 90°
R-values:
R R work R free
0.198 0.194 0.256
Expression system: Escherichia coli

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