› 1vm5

Solution NMR

Solution structure of micelle-bound aurein 1.2, an antimicrobial and anticancer peptide from an Australian frog

Released:
DOI: 10.2210/pdb1vm5/pdb
PDB entry 1vm5 coloured by chain, ensemble of 5 models, front view.
PDB entry 1vm5 coloured by chain, ensemble of 5 models, side view.
PDB entry 1vm5 coloured by chain, ensemble of 5 models, top view.
Source organism: synthetic construct
Primary publication:
Correlation of three-dimensional structures with the antibacterial activity of a group of peptides designed based on a nontoxic bacterial membrane anchor.
Wang G, Li Y, Li X
J Biol Chem 280 5803-11 (2005)
PMID: 15572363

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160628 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aurein-1.2 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.48 KDa
Source organism: synthetic construct
Expression system: Not provided
UniProt:
  • Canonical: P82387 (Residues: 1-13; Coverage: 100%)
Sequence domains: Aurein-like antibiotic peptide

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

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Citations

6 review citations

Antimicrobial peptides in 2014.
Wang et al. (2015)
5 more

8 mentions without citation

Antimicrobial Peptides as Anti-Infective Agents in Pre-Post-Antibiotic Era?
Rončević et al. (2019)
7 more