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Solution NMR

Solution Structure of the N-terminal Ras-binding Domain (RBD) in Human a-Raf Kinase

Released:
DOI: 10.2210/pdb1wxm/pdb
PDB entry 1wxm coloured by chain, ensemble of 20 models, front view.
PDB entry 1wxm coloured by chain, ensemble of 20 models, side view.
PDB entry 1wxm coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Zhao C, Tochio N, Koshiba S, Inoue M, Kigawa T, Yokoyama S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145292 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serine/threonine-protein kinase A-Raf Chain: A
Molecule details ›
Chain: A
Length: 86 amino acids
Theoretical weight: 9.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P10398 (Residues: 19-91; Coverage: 12%)
Gene names: ARAF, ARAF1, PKS, PKS2
Sequence domains: Raf-like Ras-binding domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Not provided

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