› 1wz9

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153266 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Serpin B5 Chains: A, B
Molecule details ›
Chains: A, B
Length: 375 amino acids
Theoretical weight: 42.63 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P36952 (Residues: 1-375; Coverage: 100%)
Gene names: PI5, SERPINB5
Sequence domains: Serpin (serine protease inhibitor)
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand SO4 1 x SO4
1 modified residue:
Ligand CME 12 x CME

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 54.115Å b: 95.047Å c: 139.225Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.249
Expression system: Escherichia coli BL21

Quick links

Citations

9 review citations

An overview of the serpin superfamily.
Law et al. (2006)
8 more

6 mentions without citation

A Comprehensive Phylogenetic Analysis of the Serpin Superfamily.
Spence et al. (2021)
5 more