› 1xb7

X-ray diffraction
2.5Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145852 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Steroid hormone receptor ERR1 Chain: A
Molecule details ›
Chain: A
Length: 247 amino acids
Theoretical weight: 27.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P11474 (Residues: 194-423; Coverage: 54%)
Gene names: ERR1, ESRL1, ESRRA, NR3B1
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha Chain: P
Molecule details ›
Chain: P
Length: 12 amino acids
Theoretical weight: 1.39 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: Q9UBK2 (Residues: 205-216; Coverage: 2%)
Gene names: LEM6, PGC1, PGC1A, PPARGC1, PPARGC1A

Ligands and Environments

1 bound ligand:
Ligand IOD 1 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P6522
Unit cell:
a: 109.999Å b: 109.999Å c: 104.671Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.247
Expression systems:
  • Spodoptera frugiperda
  • Not provided

Quick links

Citations

34 review citations

Transcriptional control of mitochondrial biogenesis and function.
Hock et al. (2009)
33 more

8 mentions without citation

The Role of the Estrogen-Related Receptor Alpha (ERRa) in Hypoxia and Its Implications for Cancer Metabolism.
Chaltel-Lima et al. (2023)
7 more