1xjy

X-ray diffraction
2Å resolution

The crystal structures of the DNA binding sites of the RUNX1 transcription factor

Released:
Source organism: Synthetic construct
Primary publication:
Structures of the DNA-binding site of Runt-domain transcription regulators.
Acta Crystallogr D Biol Crystallogr 61 236-46 (2005)
PMID: 15735333

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-114819 (preferred)
Entry contents:
2 distinct DNA molecules
Macromolecules (2 distinct):
5'-D(*TP*CP*TP*GP*CP*GP*GP*TP*C)-3' Chain: A
Molecule details ›
Chain: A
Length: 9 nucleotides
Theoretical weight: 2.72 KDa
Source organism: Synthetic construct
Expression system: Not provided
5'-D(*TP*GP*AP*CP*CP*GP*CP*AP*G)-3' Chain: B
Molecule details ›
Chain: B
Length: 9 nucleotides
Theoretical weight: 2.74 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P43
Unit cell:
a: 42.295Å b: 42.295Å c: 24.333Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.142 0.141 0.188
Expression system: Not provided