› 1xu6

Solution NMR

Structure of the C-terminal domain from Trypanosoma brucei Variant Surface Glycoprotein MITat1.2

Released:
DOI: 10.2210/pdb1xu6/pdb
PDB entry 1xu6 coloured by chain, ensemble of 60 models, front view.
PDB entry 1xu6 coloured by chain, ensemble of 60 models, side view.
PDB entry 1xu6 coloured by chain, ensemble of 60 models, top view.
Source organism: Trypanosoma brucei brucei
Primary publication:
Structure of the C-terminal domain from Trypanosoma brucei variant surface glycoprotein MITat1.2.
Chattopadhyay A, Jones NG, Nietlispach D, Nielsen PR, Voorheis HP, Mott HR, Carrington M
J Biol Chem 280 7228-35 (2005)
PMID: 15557330

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150699 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Variant surface glycoprotein MITAT 1.2 Chain: A
Molecule details ›
Chain: A
Length: 80 amino acids
Theoretical weight: 8.75 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Escherichia coli
UniProt:
  • Canonical: P26332 (Residues: 385-459; Coverage: 17%)
Structure domains: Variant surface glycoprotein MITAT 1.2, VSG 221, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSION ANGLE DYNAMICS, SIMULATED ANNEALING
Expression system: Escherichia coli

Quick links

Citations

12 review citations

The molecular arms race between African trypanosomes and humans.
Pays et al. (2014)
11 more

4 mentions without citation

Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei.
Mugnier et al. (2016)
3 more