› 1yej

X-ray diffraction
1.85Å resolution

CATALYTIC ANTIBODY COMPLEX

Released:
DOI: 10.2210/pdb1yej/pdb
PDB entry 1yej coloured by chain, front view.
PDB entry 1yej coloured by chain, side view.
PDB entry 1yej coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
Crossreactivity, efficiency and catalytic specificity of an esterase-like antibody.
Gigant B, Charbonnier JB, Eshhar Z, Green BS, Knossow M
J Mol Biol 284 741-50 (1998)
PMID: 9826512

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-212288 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ig-like domain-containing protein Chain: L
Molecule details ›
Chain: L
Length: 219 amino acids
Theoretical weight: 24.02 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: Q58EU8 (Residues: 21-239; Coverage: 100%)
Gene name: Igk
Sequence domains:
Structure domains: Immunoglobulins
PROTEIN (IG ANTIBODY D2.3 (HEAVY CHAIN)) Chain: H
Molecule details ›
Chain: H
Length: 222 amino acids
Theoretical weight: 24.19 KDa
Source organism: Mus musculus
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:
Ligand ZN 7 x ZN
Ligand PNF 1 x PNF
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LURE BEAMLINE DW32
Spacegroup: P3121
Unit cell:
a: 78.271Å b: 78.271Å c: 158.674Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.212 0.212 0.246

Quick links

Citations

5 citation in other articles

Bio-orthogonal affinity purification of direct kinase substrates.
Allen et al. (2005)
4 more

1 mention without citation

Antibody CDR loops as ensembles in solution vs. canonical clusters from X-ray structures.
Fernández-Quintero et al. (2020)