› 1ztm

X-ray diffraction
3.05Å resolution

Structure of the Uncleaved Paramyxovirus (hPIV3) Fusion Protein

Released:
DOI: 10.2210/pdb1ztm/pdb
PDB entry 1ztm coloured by chain, front view.
PDB entry 1ztm coloured by chain, side view.
PDB entry 1ztm coloured by chain, top view.
Source organism: Human respirovirus 3
Primary publication:
Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion protein.
Yin HS, Paterson RG, Wen X, Lamb RA, Jardetzky TS
Proc Natl Acad Sci U S A 102 9288-93 (2005)
PMID: 15964978

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domain:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139248 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Fusion glycoprotein F0 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 490 amino acids
Theoretical weight: 54.24 KDa
Source organism: Human respirovirus 3
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P06828 (Residues: 19-502; Coverage: 93%)
Gene name: F
Sequence domains: Fusion glycoprotein F0
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 2 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 5ID-B, APS BEAMLINE 32-ID
Spacegroup: P212121
Unit cell:
a: 105.56Å b: 122.17Å c: 195.71Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.217 0.264
Expression system: Trichoplusia ni

Quick links

Citations

38 review citations

Viral membrane fusion.
Harrison SC. (2008)
37 more

48 mentions without citation

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
47 more