› 2a0a

Solution NMR

Solution Structure of Der f 13, Group 13 Allergen from House Dust Mites

Released:
DOI: 10.2210/pdb2a0a/pdb
PDB entry 2a0a coloured by chain, ensemble of 10 models, front view.
PDB entry 2a0a coloured by chain, ensemble of 10 models, side view.
PDB entry 2a0a coloured by chain, ensemble of 10 models, top view.
Source organism: Dermatophagoides farinae
Primary publication:
Nuclear magnetic resonance structure-based epitope mapping and modulation of dust mite group 13 allergen as a hypoallergen.
Chan SL, Ong ST, Ong SY, Chew FT, Mok YK
J Immunol 176 4852-60 (2006)
PMID: 16585580

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172970 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lipocalin/cytosolic fatty-acid binding domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 131 amino acids
Theoretical weight: 15 KDa
Source organism: Dermatophagoides farinae
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q1M2P5 (Residues: 1-131; Coverage: 100%)
Gene names: DERF_001021, FABP5_3, HUG17_4271
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

T and B cell responses to HDM allergens and antigens.
Thomas et al. (2007)
5 more

9 mentions without citation

Relevant B cell epitopes in allergic disease.
Pomés A. (2010)
8 more