› 2ayz

Solution NMR

Solution structure of the E.coli RcsC C-terminus (residues 817-949) containing phosphoreceiver domain

Released:
DOI: 10.2210/pdb2ayz/pdb
PDB entry 2ayz coloured by chain, ensemble of 25 models, front view.
PDB entry 2ayz coloured by chain, ensemble of 25 models, side view.
PDB entry 2ayz coloured by chain, ensemble of 25 models, top view.
Source organism: Escherichia coli
Primary publication:
A new structural domain in the Escherichia coli RcsC hybrid sensor kinase connects histidine kinase and phosphoreceiver domains.
Rogov VV, Rogova NY, Bernhard F, Koglin A, Löhr F, Dötsch V
J Mol Biol 364 68-79 (2006)
PMID: 17005198

Function and Biology Details

Reaction catalysed: 
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143637 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sensor histidine kinase RcsC Chain: A
Molecule details ›
Chain: A
Length: 133 amino acids
Theoretical weight: 14.74 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0DMC5 (Residues: 817-949; Coverage: 14%)
Gene names: JW5917/JW5920, b2218, rcsC
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: Energy minimization
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The Complex Rcs Regulatory Cascade.
Wall et al. (2018)
1 more

1 mention without citation

Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways.
Schulman et al. (2009)