› 2dcx

Solution NMR

NMR solution structure of the Dermaseptin antimicrobial peptide analog NC12-K4S4(1-13)a

Released:
DOI: 10.2210/pdb2dcx/pdb
PDB entry 2dcx coloured by chain, ensemble of 15 models, front view.
PDB entry 2dcx coloured by chain, ensemble of 15 models, side view.
PDB entry 2dcx coloured by chain, ensemble of 15 models, top view.
Source organism: Phyllomedusa sauvagii
Primary publication:
Consequences of N-acylation on structure and membrane binding properties of dermaseptin derivative K4-S4-(1-13).
Shalev DE, Rotem S, Fish A, Mor A
J Biol Chem 281 9432-8 (2006)
PMID: 16407175

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160381 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dermaseptin-S4 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.51 KDa
Source organism: Phyllomedusa sauvagii
Expression system: Not provided
UniProt:
  • Canonical: P80280 (Residues: 1-13; Coverage: 48%)

Ligands and Environments

1 bound ligand:
Ligand DOA 1 x DOA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: Distance Geometry, Simulated Annealing
Expression system: Not provided

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Citations

6 review citations

Peptides and Peptidomimetics for Antimicrobial Drug Design.
Mojsoska et al. (2015)
5 more

2 mentions without citation

Antimicrobial Peptides As Biologic and Immunotherapeutic Agents against Cancer: A Comprehensive Overview.
Roudi et al. (2017)
1 more