› 2dsw

X-ray diffraction
2.8Å resolution

Binding of chitin-like polysaccharides to protective signalling factor: crystal structure of the complex of signalling protein from sheep (SPS-40) with a pentasaccharide at 2.8 A resolution

Released:
DOI: 10.2210/pdb2dsw/pdb
PDB entry 2dsw coloured by chain, front view.
PDB entry 2dsw coloured by chain, side view.
PDB entry 2dsw coloured by chain, top view.
Source organism: Ovis aries
Primary publication:
Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides.
Srivastava DB, Ethayathulla AS, Kumar J, Somvanshi RK, Sharma S, Dey S, Singh TP
J Struct Biol 158 255-66 (2007)
PMID: 17188513

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-180381 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (3 distinct):
Chitinase-3-like protein 1 Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 40.61 KDa
Source organism: Ovis aries
UniProt:
  • Canonical: Q6TMG6 (Residues: 1-361; Coverage: 100%)
Gene name: CHI3L1
Sequence domains: Glycosyl hydrolases family 18
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 62.66Å b: 66.48Å c: 107.526Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.199 0.219

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Citations

2 review citations

Survey of the year 2007 commercial optical biosensor literature.
Rich et al. (2008)
1 more