Function and Biology Details
Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
F-box only protein 2 and Ribonuclease pancreatic (preferred)
PDBe Complex ID:
PDB-CPX-158393 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (3 distinct):
F-box only protein 2
Molecule details ›
Chain: A
Length: 197 amino acids
Theoretical weight: 22.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
Sequence domains: F-box associated region
Structure domains: Galactose-binding domain-like
Length: 197 amino acids
Theoretical weight: 22.59 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
- Canonical:
Q80UW2 (Residues: 105-297; Coverage: 65%)
Sequence domains: F-box associated region
Structure domains: Galactose-binding domain-like
Ribonuclease pancreatic
Molecule details ›
Chain: B
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
- Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain
Ligands and Environments
Experiments and Validation Details
X-ray source:
SPRING-8 BEAMLINE BL44XU
Spacegroup:
P432
Expression system: Escherichia coli
