› 2f2b

X-ray diffraction
1.68Å resolution

Crystal structure of integral membrane protein Aquaporin AqpM at 1.68A resolution

Released:
DOI: 10.2210/pdb2f2b/pdb
PDB entry 2f2b coloured by chain, front view.
PDB entry 2f2b coloured by chain, side view.
PDB entry 2f2b coloured by chain, top view.
Source organism: Methanothermobacter marburgensis str. Marburg
Primary publication:
Structural basis for conductance by the archaeal aquaporin AqpM at 1.68 A.
Lee JK, Kozono D, Remis J, Kitagawa Y, Agre P, Stroud RM
Proc Natl Acad Sci U S A 102 18932-7 (2005)
PMID: 16361443

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189909 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aquaporin AqpM Chain: A
Molecule details ›
Chain: A
Length: 246 amino acids
Theoretical weight: 25.36 KDa
Source organism: Methanothermobacter marburgensis str. Marburg
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9C4Z5 (Residues: 1-246; Coverage: 100%)
Gene names: MTBMA_c05510, aqpM
Sequence domains: Major intrinsic protein
Structure domains: Glycerol uptake facilitator protein.

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: I4
Unit cell:
a: 88.513Å b: 88.513Å c: 79.947Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.184 0.193
Expression system: Escherichia coli

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Citations

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