2fgw

X-ray diffraction
3Å resolution

X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-213144 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H52 FAB (LIGHT CHAIN) Chain: L
Molecule details ›
Chain: L
Length: 214 amino acids
Theoretical weight: 23.47 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins
H52 FAB (HEAVY CHAIN) Chain: H
Molecule details ›
Chain: H
Length: 232 amino acids
Theoretical weight: 24.98 KDa
Source organism: Homo sapiens
Expression system: Not provided
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P3
Unit cell:
a: 101Å b: 101Å c: 45.5Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.176 not available
Expression system: Not provided