2g4s

X-ray diffraction
2.15Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
PDBe Complex ID:
PDB-CPX-172040 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Next to BRCA1 gene 1 protein Chain: A
Molecule details ›
Chain: A
Length: 86 amino acids
Theoretical weight: 9.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14596 (Residues: 1-85; Coverage: 9%)
Gene names: 1A13B, KIAA0049, M17S2, MIG19, NBR1
Sequence domains: PB1 domain
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: P6322
Unit cell:
a: 101.4Å b: 101.4Å c: 42.59Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.214 0.323
Expression system: Escherichia coli