Function and Biology Details
Reaction catalysed:
ATP + [biotin carboxyl-carrier protein]-biotin-N(6)-L-lysine + hydrogencarbonate- = ADP + phosphate + [biotin carboxyl-carrier protein]-carboxybiotin-N(6)-L-lysine
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain
- Biotin carboxylase, C-terminal
- Rudiment single hybrid motif
- ATP-grasp fold, subdomain 1
- ATP-grasp fold
- Biotin carboxylation domain
- Biotin carboxylase-like, N-terminal domain
- Acetyl-CoA carboxylase, biotin carboxylase
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
monomeric (preferred)
Assembly name:
Biotin carboxylase (preferred)
PDBe Complex ID:
PDB-CPX-150165 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Biotin carboxylase
Molecule details ›
Chains: A, B, C, D
Length: 469 amino acids
Theoretical weight: 51.48 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 469 amino acids
Theoretical weight: 51.48 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P24182 (Residues: 1-449; Coverage: 100%)
Sequence domains:
- Biotin carboxylase, N-terminal domain
- Carbamoyl-phosphate synthase L chain, ATP binding domain
- Biotin carboxylase C-terminal domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
NSLS BEAMLINE X29A
Spacegroup:
P21
Expression system: Escherichia coli
