› 2h3k

Solution NMR

Solution Structure of the first NEAT domain of IsdH

Released:
DOI: 10.2210/pdb2h3k/pdb
PDB entry 2h3k coloured by chain, ensemble of 20 models, front view.
PDB entry 2h3k coloured by chain, ensemble of 20 models, side view.
PDB entry 2h3k coloured by chain, ensemble of 20 models, top view.
Source organism: Staphylococcus aureus subsp. aureus MSSA476
Primary publication:
Solution structure of the NEAT (NEAr Transporter) domain from IsdH/HarA: the human hemoglobin receptor in Staphylococcus aureus.
Pilpa RM, Fadeev EA, Villareal VA, Wong ML, Phillips M, Clubb RT
J Mol Biol 360 435-47 (2006)
PMID: 16762363

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179651 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Iron-regulated surface determinant protein H Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.73 KDa
Source organism: Staphylococcus aureus subsp. aureus MSSA476
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q6G8J7 (Residues: 86-229; Coverage: 17%)
Gene names: SAS1657, harA, isdH, sasI
Sequence domains: Iron Transport-associated domain
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 79%
Refinement method: distance geometry
Expression system: Escherichia coli BL21

Quick links

Citations

9 review citations

Recent developments in understanding the iron acquisition strategies of gram positive pathogens.
Sheldon et al. (2015)
8 more

6 mentions without citation

Updates to the Integrated Protein-Protein Interaction Benchmarks: Docking Benchmark Version 5 and Affinity Benchmark Version 2.
Vreven et al. (2015)
5 more