› 2h70

X-ray diffraction
2.7Å resolution

Crystal Structure of Thioredoxin Mutant D9E in Hexagonal (p61) Space Group

Released:
DOI: 10.2210/pdb2h70/pdb
PDB entry 2h70 coloured by chain, front view.
PDB entry 2h70 coloured by chain, side view.
PDB entry 2h70 coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.
Godoy-Ruiz R, Perez-Jimenez R, Ibarra-Molero B, Sanchez-Ruiz JM
Biophys J 89 3320-31 (2005)
PMID: 16100262

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 11.7 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P0AA25 (Residues: 2-109; Coverage: 99%)
Gene names: JW5856, b3781, fipA, trxA, tsnC
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand MPD 3 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P61
Unit cell:
a: 103.026Å b: 103.026Å c: 40.279Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.21 0.206 0.292
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Biliverdin reductase: PKC interaction at the cross-talk of MAPK and PI3K signaling pathways.
Maines MD. (2007)
14 other articles

2 mentions without citation

Binding interface prediction by combining protein-protein docking results.
Hwang et al. (2014)
1 more