› 2hox

X-ray diffraction
1.4Å resolution

Function and Biology Details

Reaction catalysed: 
An S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo dimer
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169604 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (6 distinct):
Alliin lyase 1 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 427 amino acids
Theoretical weight: 49.06 KDa
Source organism: Allium sativum
UniProt:
  • Canonical: Q01594 (Residues: 39-465; Coverage: 93%)
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, BMA, XYP, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, BMA, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
3 bound ligands:
Ligand NAG 8 x NAG
Ligand CL 4 x CL
Ligand P1T 4 x P1T
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: P21
Unit cell:
a: 67.665Å b: 126.892Å c: 102.664Å
α: 90° β: 97.3° γ: 90°
R-values:
R R work R free
0.169 0.167 0.205

Quick links

Citations

5 review citations

Chemical Constituents and Pharmacological Activities of Garlic (Allium sativum L.): A Review.
El-Saber Batiha et al. (2020)
4 more

7 mentions without citation

Rapid synthesis of auxin via a new tryptophan-dependent pathway is required for shade avoidance in plants.
Tao et al. (2008)
6 more