› 2hrf

Solution NMR

Solution Structure of Cu(I) P174L HSco1

Released:
DOI: 10.2210/pdb2hrf/pdb
PDB entry 2hrf coloured by chain, front view.
PDB entry 2hrf coloured by chain, side view.
PDB entry 2hrf coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Human Sco1 functional studies and pathological implications of the P174L mutant.
Banci L, Bertini I, Ciofi-Baffoni S, Leontari I, Martinelli M, Palumaa P, Sillard R, Wang S
Proc Natl Acad Sci U S A 104 15-20 (2007)
PMID: 17182746

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131151 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein SCO1 homolog, mitochondrial Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 19.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O75880 (Residues: 132-301; Coverage: 57%)
Gene names: SCO1, SCOD1
Sequence domains: SCO1/SenC
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand CU1 1 x CU1
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

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Citations

34 review citations

Copper metallochaperones.
Robinson et al. (2010)
33 more