› 2ixl

X-ray diffraction
1.6Å resolution

Function and Biology Details

Reaction catalysed: 
dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184524 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
dTDP-4-dehydrorhamnose 3,5-epimerase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 197 amino acids
Theoretical weight: 22.49 KDa
Source organism: Streptococcus suis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q8GIQ0 (Residues: 1-197; Coverage: 100%)
Gene names: ERS156295_00910, rfbC, rmlC
Sequence domains: dTDP-4-dehydrorhamnose 3,5-epimerase
Structure domains: Jelly Rolls

Ligands and Environments

2 bound ligands:
Ligand TRH 4 x TRH
Ligand NI 2 x NI
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 51.408Å b: 141.526Å c: 53.586Å
α: 90° β: 92.57° γ: 90°
R-values:
R R work R free
0.169 0.167 0.212
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Review: Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa.
King et al. (2009)
8 more

3 mentions without citation

Rhamnose-Containing Compounds: Biosynthesis and Applications.
Li et al. (2022)
2 more