› 2jwh

Solution NMR

Structure of a Glycosylphosphatidylinositol-anchored Domain from a Trypanosome Variant Surface Glycoprotein

Released:
DOI: 10.2210/pdb2jwh/pdb
PDB entry 2jwh coloured by chain, ensemble of 35 models, front view.
PDB entry 2jwh coloured by chain, ensemble of 35 models, side view.
PDB entry 2jwh coloured by chain, ensemble of 35 models, top view.
Source organism: Trypanosoma brucei brucei
Primary publication:
Structure of a glycosylphosphatidylinositol-anchored domain from a trypanosome variant surface glycoprotein.
Jones NG, Nietlispach D, Sharma R, Burke DF, Eyres I, Mues M, Mott HR, Carrington M
J Biol Chem 283 3584-3593 (2008)
PMID: 18003615

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150695 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Variant surface glycoprotein ILTAT 1.24 Chain: A
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 4.93 KDa
Source organism: Trypanosoma brucei brucei
Expression system: Escherichia coli
UniProt:
  • Canonical: P26329 (Residues: 445-491; Coverage: 10%)
Sequence domains: Trypanosome variant surface glycoprotein C-terminal domain
Structure domains: ligand-binding face of the semaphorins, domain 2

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Genetic and epigenetic mechanisms underlying cell-surface variability in protozoa and fungi.
Verstrepen et al. (2009)
10 more