› 2kwq

Solution NMR

Mcm10 C-terminal DNA binding domain

Released:
DOI: 10.2210/pdb2kwq/pdb
PDB entry 2kwq coloured by chain, ensemble of 20 models, front view.
PDB entry 2kwq coloured by chain, ensemble of 20 models, side view.
PDB entry 2kwq coloured by chain, ensemble of 20 models, top view.
Source organism: Xenopus laevis
Primary publication:
Solution NMR structure of the C-terminal DNA binding domain of Mcm10 reveals a conserved MCM motif.
Robertson PD, Chagot B, Chazin WJ, Eichman BF
J Biol Chem 285 22942-9 (2010)
PMID: 20489205

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177011 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein MCM10 homolog Chain: A
Molecule details ›
Chain: A
Length: 92 amino acids
Theoretical weight: 10.6 KDa
Source organism: Xenopus laevis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5EAW4 (Residues: 755-842; Coverage: 10%)
Gene name: mcm10

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 80%
Refinement method: molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Enigmatic roles of Mcm10 in DNA replication.
Thu et al. (2013)
4 more

3 mentions without citation

Mcm10: A Dynamic Scaffold at Eukaryotic Replication Forks.
Baxley et al. (2017)
2 more