› 2lfb

Solution NMR

HOMEODOMAIN FROM RAT LIVER LFB1/HNF1 TRANSCRIPTION FACTOR, NMR, 20 STRUCTURES

Released:
DOI: 10.2210/pdb2lfb/pdb
PDB entry 2lfb coloured by chain, ensemble of 20 models, front view.
PDB entry 2lfb coloured by chain, ensemble of 20 models, side view.
PDB entry 2lfb coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus rattus
Primary publication:
The NMR solution structure of the non-classical homeodomain from the rat liver LFB1/HNF1 transcription factor.
Schott O, Billeter M, Leiting B, Wider G, Wüthrich K
J Mol Biol 267 673-83 (1997)
PMID: 9126845

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-147283 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Hepatocyte nuclear factor 1-alpha Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 11.81 KDa
Source organism: Rattus rattus
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P15257 (Residues: 195-286; Coverage: 15%)
Gene names: Hnf-1, Hnf-1a, Hnf1a, Tcf1
Structure domains: Homeodomain-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY WITH DIANA, ENERGY MINIMIZATION WITH OPAL
Expression system: Escherichia coli BL21

Quick links

Citations

1 review citation

Hepatocyte nuclear factor-1β: A regulator of kidney development and cystogenesis.
Singh et al. (2015)
8 other articles

1 mention without citation

The effects of rigid motions on elastic network model force constants.
Lezon TR. (2012)