› 2mnf

Solution NMR

AIK-18/51 DNA recognition sequence d(CGACTAGTCG)2

Released:
DOI: 10.2210/pdb2mnf/pdb
PDB entry 2mnf coloured by chain, front view.
PDB entry 2mnf coloured by chain, side view.
PDB entry 2mnf coloured by chain, top view.
Source organism: Synthetic construct
Primary publication:
Recognition of the DNA minor groove by thiazotropsin analogues.
Alniss HY, Salvia MV, Sadikov M, Golovchenko I, Anthony NG, Khalaf AI, MacKay SP, Suckling CJ, Parkinson JA
Chembiochem 15 1978-90 (2014)
PMID: 25045155

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115634 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
5'-D(*CP*GP*AP*CP*TP*AP*GP*TP*CP*G)-3' Chains: A, B
Molecule details ›
Chains: A, B
Length: 10 nucleotides
Theoretical weight: 3.05 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 19%
Refinement method: molecular dynamics
Expression system: Not provided

Quick links

Citations

1 review citation

An overview of recent advances in duplex DNA recognition by small molecules.
Bhaduri et al. (2018)
7 other articles