› 2mvy

Solution NMR

Structure and Stability of RNAs Containing N6-Methyl-adenosine

Released:
DOI: 10.2210/pdb2mvy/pdb
PDB entry 2mvy coloured by chain, front view.
PDB entry 2mvy coloured by chain, side view.
PDB entry 2mvy coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.
Roost C, Lynch SR, Batista PJ, Qu K, Chang HY, Kool ET
J Am Chem Soc 137 2107-15 (2015)
PMID: 25611135

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196509 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA Chains: 1, 2
Molecule details ›
Chains: 1, 2
Length: 10 nucleotides
Theoretical weight: 3.18 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 29%
Refinement method: simulated annealing, molecular dynamics
Expression system: Not provided

Quick links

Citations

112 review citations

Dynamic RNA Modifications in Gene Expression Regulation.
Roundtree et al. (2017)
111 more

2 mentions without citation

Structure and thermodynamics of N6-methyladenosine in RNA: a spring-loaded base modification.
Roost et al. (2015)
1 more