Function and Biology Details
Reactions catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
- not assigned
Biological process:
Cellular component:
- not assigned
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-128906 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Tumor necrosis factor receptor superfamily member 16
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Death domain
Structure domains: Death Domain, Fas
Length: 98 amino acids
Theoretical weight: 10.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
P08138 (Residues: 330-427; Coverage: 25%)
Sequence domains: Death domain
Structure domains: Death Domain, Fas
Receptor-interacting serine/threonine-protein kinase 2
Molecule details ›
Chain: B
Length: 106 amino acids
Theoretical weight: 12.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: Caspase recruitment domain
Length: 106 amino acids
Theoretical weight: 12.12 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: O43353 (Residues: 434-539; Coverage: 20%)
Sequence domains: Caspase recruitment domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
83%
Refinement method:
molecular dynamics
Expression system: Escherichia coli
