› 2o2t

X-ray diffraction
2.7Å resolution

The crystal structure of the 1st PDZ domain of MPDZ

Released:
DOI: 10.2210/pdb2o2t/pdb
PDB entry 2o2t coloured by chain, front view.
PDB entry 2o2t coloured by chain, side view.
PDB entry 2o2t coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Papagrigoriou E, Gileadi C, Phillips C, Johansson C, Salah E, Savitsky P, Gorrec F, Umeano C, Berridge G, Pike ACW, Elkins J, Edwards A, Arrowsmith C, Weigelt J, Sundstrom M, Doyle DA, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131185 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Multiple PDZ domain protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 117 amino acids
Theoretical weight: 12.9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O75970 (Residues: 117-227; Coverage: 5%)
Gene names: MPDZ, MUPP1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 100.366Å b: 32.66Å c: 92.803Å
α: 90° β: 110.68° γ: 90°
R-values:
R R work R free
0.227 0.224 0.291
Expression system: Escherichia coli BL21(DE3)

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