› 2odu

X-ray diffraction
2.3Å resolution

Crystal structure of a fragment of the plakin domain of plectin

Released:
DOI: 10.2210/pdb2odu/pdb
PDB entry 2odu coloured by chain, front view.
PDB entry 2odu coloured by chain, side view.
PDB entry 2odu coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
The structure of a tandem pair of spectrin repeats of plectin reveals a modular organization of the plakin domain.
Sonnenberg A, Rojas AM, de Pereda JM
J Mol Biol 368 1379-91 (2007)
PMID: 17397861

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172226 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plectin Chain: A
Molecule details ›
Chain: A
Length: 235 amino acids
Theoretical weight: 27.48 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15149 (Residues: 410-640; Coverage: 5%)
Gene names: PLEC, PLEC1
Sequence domains: Spectrin-like repeat
Structure domains: Methane Monooxygenase Hydroxylase; Chain G, domain 1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P21212
Unit cell:
a: 154.15Å b: 26.34Å c: 58.23Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.219 0.216 0.269
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

16 review citations

Introducing intermediate filaments: from discovery to disease.
Eriksson et al. (2009)
15 more

4 mentions without citation

Advances and perspectives of the architecture of hemidesmosomes: lessons from structural biology.
de Pereda et al. (2009)
3 more