› 2p7r

Solution NMR

Cyclic pentapeptide which inhibits Hantavirus

Released:
DOI: 10.2210/pdb2p7r/pdb
PDB entry 2p7r coloured by chain, ensemble of 11 models, front view.
PDB entry 2p7r coloured by chain, ensemble of 11 models, side view.
PDB entry 2p7r coloured by chain, ensemble of 11 models, top view.
Source organism: Synthetic construct
Primary publication:
Characterization and NMR solution structure of a novel cyclic pentapeptide inhibitor of pathogenic hantaviruses.
Hall PR, Malone L, Sillerud LO, Ye C, Hjelle BL, Larson RS
Chem Biol Drug Des 69 180-90 (2007)
PMID: 17441904

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163149 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
cyclo-CPFVC Chain: A
Molecule details ›
Chain: A
Length: 5 amino acids
Theoretical weight: 568 Da
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

7 review citations

Human pathogenic hantaviruses and prevention of infection.
Krüger et al. (2011)
6 more

2 mentions without citation

Coarse-Graining ddCOSMO through an Interface between Tinker and the ddX Library.
Nottoli et al. (2022)
1 more