› 2q9b

X-ray diffraction
2.3Å resolution

Structure of FTSY:GMPPNP Complex

Released:
DOI: 10.2210/pdb2q9b/pdb
PDB entry 2q9b coloured by chain, front view.
PDB entry 2q9b coloured by chain, side view.
PDB entry 2q9b coloured by chain, top view.
Source organism: Thermus aquaticus
Primary publication:
X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates.
Reyes CL, Rutenber E, Walter P, Stroud RM
OpenAccess logo PLoS One 2 e607 (2007)
PMID: 17622352

Function and Biology Details

Reaction catalysed: 
GTP + H(2)O = GDP + phosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-160736 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Signal recognition particle receptor FtsY Chains: A, B
Molecule details ›
Chains: A, B
Length: 304 amino acids
Theoretical weight: 33.1 KDa
Source organism: Thermus aquaticus
Expression system: Escherichia coli
UniProt:
  • Canonical: P83749 (Residues: 1-304; Coverage: 100%)
Gene name: ftsY
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
Ligand SO4 8 x SO4
Ligand EDO 9 x EDO
Ligand GNP 1 x GNP
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-1
Spacegroup: P212121
Unit cell:
a: 63.843Å b: 97.298Å c: 99.284Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.208 0.208 0.269
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Protein translocation across the bacterial cytoplasmic membrane.
Driessen et al. (2008)
3 more

4 mentions without citation

A tale of two GTPases in cotranslational protein targeting.
Saraogi et al. (2011)
3 more