› 2qsp

X-ray diffraction
1.85Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
hetero tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-135382 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Hemoglobin subunit alpha Chains: A, C
Molecule details ›
Chains: A, C
Length: 141 amino acids
Theoretical weight: 15.08 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P01966 (Residues: 2-142; Coverage: 99%)
Gene name: HBA
Sequence domains: Globin
Structure domains: Globins
Hemoglobin subunit beta Chains: B, D
Molecule details ›
Chains: B, D
Length: 145 amino acids
Theoretical weight: 15.98 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P02070 (Residues: 1-145; Coverage: 100%)
Gene name: HBB
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

1 bound ligand:
Ligand HEM 4 x HEM
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BRUKER AXS MICROSTAR
Spacegroup: P212121
Unit cell:
a: 65.033Å b: 78.273Å c: 109.085Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.19 0.187 0.258

Quick links

Citations

6 review citations

Structure and reactivity of hexacoordinate hemoglobins.
Kakar et al. (2010)
5 more

5 mentions without citation

Challenging Density Functional Theory Calculations with Hemes and Porphyrins.
de Visser et al. (2016)
4 more