› 2rd3

X-ray diffraction
2.7Å resolution

Crystal structure of TenA homologue (HP1287) from Helicobacter pylori

Released:
DOI: 10.2210/pdb2rd3/pdb
PDB entry 2rd3 coloured by chain, front view.
PDB entry 2rd3 coloured by chain, side view.
PDB entry 2rd3 coloured by chain, top view.
Source organism: Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093
Entry authors: Barison N, Cendron L, Trento A, Angelini A, Zanotti G

Function and Biology Details

Reaction catalysed: 
4-amino-5-aminomethyl-2-methylpyrimidine + H(2)O = 4-amino-5-hydroxymethyl-2-methylpyrimidine + ammonia
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo tetramer
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108730 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Aminopyrimidine aminohydrolase Chains: A, D
Molecule details ›
Chains: A, D
Length: 223 amino acids
Theoretical weight: 25.67 KDa
Source organism: Helicobacter pylori NCTC 11637 = CCUG 17874 = ATCC 43504 = JCM 12093
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: A8KRL3 (Residues: 1-217; Coverage: 100%)
Gene name: tenA
Sequence domains: TENA/THI-4/PQQC family
Structure domains: Heme oxygenase-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I4122
Unit cell:
a: 148.42Å b: 148.42Å c: 233.525Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.236 0.235 0.258
Expression system: Escherichia coli BL21(DE3)

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