Function and Biology Details
Reaction catalysed:
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero tetramer (preferred)
Assembly name:
Tyrosine--tRNA ligase, mitochondrial and RNA (preferred)
PDBe Complex ID:
PDB-CPX-250172 (preferred)
Entry contents:
1 distinct polypeptide molecule
2 distinct RNA molecules
2 distinct RNA molecules
Macromolecules (3 distinct):
Tyrosine--tRNA ligase, mitochondrial
Molecule details ›
Chains: A, B, E, F, I, J, M, N
Length: 392 amino acids
Theoretical weight: 44.92 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli
UniProt:
Sequence domains: tRNA synthetases class I (W and Y)
Length: 392 amino acids
Theoretical weight: 44.92 KDa
Source organism: Neurospora crassa
Expression system: Escherichia coli
UniProt:
- Canonical:
P12063 (Residues: 33-423; Coverage: 58%)
Sequence domains: tRNA synthetases class I (W and Y)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
APS BEAMLINE 23-ID-D
Spacegroup:
P2
Expression systems:
- Escherichia coli
- Staphylococcus virus Twort
- Not provided
