› 2spt

X-ray diffraction
2.5Å resolution

DIFFERENCES IN THE METAL ION STRUCTURE BETWEEN SR-AND CA-PROTHROMBIN FRAGMENT 1

Released:
DOI: 10.2210/pdb2spt/pdb
PDB entry 2spt coloured by chain, front view.
PDB entry 2spt coloured by chain, side view.
PDB entry 2spt coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Differences in the metal ion structure between Sr- and Ca-prothrombin fragment 1.
Seshadri TP, Skrzypczak-Jankun E, Yin M, Tulinsky A
Biochemistry 33 1087-92 (1994)
PMID: 8110739

Function and Biology Details

Reaction catalysed: 
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133162 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Activation peptide fragment 1 Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 16.73 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P00735 (Residues: 44-188; Coverage: 24%)
Gene name: F2
Sequence domains:
Structure domains: Plasminogen Kringle 4

Ligands and Environments

2 bound ligands:
Ligand NAG 1 x NAG
Ligand SR 8 x SR
1 modified residue:
Ligand CGU 10 x CGU

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 39.69Å b: 54.12Å c: 131.17Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.167 not available not available
Expression system: Not provided

Quick links

Citations

2 citation in other articles

Structural test of the parameterized-backbone method for protein design.
Plecs et al. (2004)
1 more

2 mentions without citation

An Algorithm for Protein Helix Assignment Using Helix Geometry.
Cao et al. (2015)
1 more