› 2v3t

X-ray diffraction
2.75Å resolution

Structure of the ligand-binding core of the ionotropic glutamate receptor-like GluRdelta2 in the apo form

Released:
DOI: 10.2210/pdb2v3t/pdb
PDB entry 2v3t coloured by chain, front view.
PDB entry 2v3t coloured by chain, side view.
PDB entry 2v3t coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.
Naur P, Hansen KB, Kristensen AS, Dravid SM, Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis SF, Kastrup JS
Proc Natl Acad Sci U S A 104 14116-21 (2007)
PMID: 17715062

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-179001 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutamate receptor ionotropic, delta-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 265 amino acids
Theoretical weight: 30.27 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q63226 (Residues: 440-813; Coverage: 27%)
Gene name: Grid2
Sequence domains:
Structure domains: Periplasmic binding protein-like II

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
1 modified residue:
Ligand MSE 14 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X12
Spacegroup: I212121
Unit cell:
a: 70.971Å b: 91.031Å c: 177.393Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.231 0.231 0.287
Expression system: Escherichia coli

Quick links

Citations

28 review citations

Glutamate receptor ion channels: structure, regulation, and function.
Traynelis et al. (2010)
27 more

6 mentions without citation

Ionotropic glutamate-like receptor delta2 binds D-serine and glycine.
Naur et al. (2007)
5 more