› 2wj5

X-ray diffraction
1.12Å resolution

Rat alpha crystallin domain

Released:
DOI: 10.2210/pdb2wj5/pdb
PDB entry 2wj5 coloured by chain, front view.
PDB entry 2wj5 coloured by chain, side view.
PDB entry 2wj5 coloured by chain, top view.
Source organism: Rattus norvegicus
Primary publication:
Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20.
Bagnéris C, Bateman OA, Naylor CE, Cronin N, Boelens WC, Keep NH, Slingsby C
J Mol Biol 392 1242-52 (2009)
PMID: 19646995

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161313 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Heat shock protein beta-6 Chain: A
Molecule details ›
Chain: A
Length: 101 amino acids
Theoretical weight: 10.84 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: P97541 (Residues: 65-162; Coverage: 61%)
Gene name: Hspb6
Sequence domains: Hsp20/alpha crystallin family
Structure domains: Immunoglobulin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: DIAMOND BEAMLINE I04
Spacegroup: C2
Unit cell:
a: 105.479Å b: 37.964Å c: 28.081Å
α: 90° β: 91.55° γ: 90°
R-values:
R R work R free
0.154 0.152 0.18
Expression system: Escherichia coli

Quick links

Citations

33 review citations

A first line of stress defense: small heat shock proteins and their function in protein homeostasis.
Haslbeck et al. (2015)
32 more

24 mentions without citation

Small heat shock proteins: Simplicity meets complexity.
Haslbeck et al. (2019)
23 more