› 2wp4

X-ray diffraction
2.49Å resolution

crystal structure of Rv3119 from Mycobacterium tuberculosis

Released:
DOI: 10.2210/pdb2wp4/pdb
PDB entry 2wp4 coloured by chain, front view.
PDB entry 2wp4 coloured by chain, side view.
PDB entry 2wp4 coloured by chain, top view.
Source organism: Mycobacterium tuberculosis
Entry authors: Cho HJ, Kang BS

Function and Biology Details

Reaction catalysed: 
Cyclic pyranopterin phosphate + 2 [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + H(2)O = molybdopterin + 2 [molybdopterin-synthase sulfur-carrier protein]
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161706 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Molybdopterin synthase catalytic subunit 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 147 amino acids
Theoretical weight: 15.94 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WJR3 (Residues: 1-147; Coverage: 100%)
Gene names: MTCY164.29, Rv3119, moaE, moaE1
Sequence domains: MoaE protein
Structure domains: Molybdopterin biosynthesis MoaE subunit

Ligands and Environments

2 bound ligands:
Ligand GOL 1 x GOL
Ligand CA 1 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P212121
Unit cell:
a: 62.464Å b: 64.353Å c: 91.928Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.2 0.247
Expression system: Escherichia coli BL21(DE3)

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