› 2wqu

X-ray diffraction
2.6Å resolution

Internalin domain of Listeria monocytogenes InlB: triclinic crystal form

Released:
DOI: 10.2210/pdb2wqu/pdb
PDB entry 2wqu coloured by chain, front view.
PDB entry 2wqu coloured by chain, side view.
PDB entry 2wqu coloured by chain, top view.
Source organism: Listeria monocytogenes EGD-e
Primary publication:
Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB.
Ferraris DM, Gherardi E, Di Y, Heinz DW, Niemann HH
J Mol Biol 395 522-32 (2010)
PMID: 19900460

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-144108 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Internalin B Chains: A, B, C, D, E, F
Molecule details ›
Chains: A, B, C, D, E, F
Length: 289 amino acids
Theoretical weight: 32.24 KDa
Source organism: Listeria monocytogenes EGD-e
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P0DQD2 (Residues: 36-321; Coverage: 48%)
Gene names: inlB, lmo0434
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 17 x SO4
Ligand GOL 3 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-2
Spacegroup: P1
Unit cell:
a: 59.66Å b: 70.65Å c: 124.66Å
α: 74.47° β: 83.13° γ: 85.65°
R-values:
R R work R free
0.194 0.191 0.249
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

9 review citations

Targeting MET in cancer: rationale and progress.
Gherardi et al. (2012)
8 more

1 mention without citation

Resveratrol-Schiff Base Hybrid Compounds with Selective Antibacterial Activity: Synthesis, Biological Activity, and Computational Study.
Sánchez-González et al. (2022)